Final rule, effective Jan 1, 2027Washington Health Care Authority
Six-month eligibility checks for medical assistance coming under federal law
The Washington Health Care Authority has amended its rules to match two federal laws that take effect January 1, 2027. One requires states to check eligibility for certain federally funded medical assistance every six months. The other shortens the retroactive coverage period for that assistance.
- Published
- Oct 7, 2026
- Effective
- Jan 1, 2027
How to weigh in: No comment period: this is a final rule.
WSR 26-19-026
ProposedWashington Department of Health
Proposed hospital price transparency rules would set reporting standards
The Washington Department of Health proposes a new section of the state administrative code, WAC 246-320-148, on hospital price transparency. It would explain how the department will decide whether hospitals meet the requirements of state law (RCW 70.41.560) on reporting prices and cost data for services and items. It would also give hospitals some flexibility to reduce repetitive reporting.
- Published
- Oct 7, 2026
- Comments close
- Oct 27, 2026
How to weigh in: Comment by October 27, 2026.
WSR 26-19-041
Temporary rule, in effectWashington Department of Health
Synthetic benzodiazepines added to Schedule I in Washington
Temporary rules in effect since September 15, 2026 place synthetic benzodiazepines in Schedule I, the category under the Controlled Substances Act, in Washington's drug rules. The Washington Department of Health says this follows federal action by the United States Drug Enforcement Administration (DEA) on clonazolam, diclazepam, etizolam, flualprazolam, flubromazolam and bromazolam.
- Published
- Oct 7, 2026
- Effective
- Sep 15, 2026
How to weigh in: No comment period: this is a final rule.
WSR 26-19-064
Temporary rule, in effectWashington Health Care Authority
Temporary rules set Apple Health coverage for adults with certain immigration status
Temporary rules in effect from September 16, 2026 govern the Washington Health Care Authority's Apple Health expansion program. The program covers adults age 19 and older who have an immigration status that makes them ineligible for medicaid or federal subsidies through the health benefit exchange, and who are not eligible for another full-scope federally funded medical assistance program. It began in 2024 under 2023 state legislation, and the temporary rules apply while permanent rules are developed.
- Published
- Oct 7, 2026
- Effective
- Sep 16, 2026
How to weigh in: No comment period: this is a final rule.
WSR 26-19-077
ProposedWashington Health Care Authority
Proposed coverage rule changes to meet federal interoperability rule
The Washington Health Care Authority proposes amendments to its rules on requests for noncovered health care services and on fee-for-service medical and dental coverage. The changes would bring the rules in line with federal rule CMS-0057-F, titled Advancing Interoperability and Improving Authorization.
- Published
- Oct 7, 2026
- Comments close
- Oct 27, 2026
How to weigh in: Comment by October 27, 2026.
WSR 26-19-090
ProposedWashington Department of Health
Proposed changes to prescription label accessibility rules
The commission, under the Washington Department of Health, proposes amendments to its prescription labeling accessibility rules. The rules require dispensing facilities and dispensing practitioners to provide accessible prescription labels on request to patients with visual impairments or print disabilities, and to patients with limited English proficiency (LEP), at no additional cost. The proposal changes which accessibility methods must be used to best meet each patient's needs; the original rules were adopted in 2025 with a 2027 effective date.
- Published
- Oct 7, 2026
- Comments close
- Oct 22, 2026
How to weigh in: Comment by October 22, 2026.
WSR 26-19-097
ProposedWashington Health Care Authority
Proposed rules would set up statewide certified behavioral health clinics
The Washington Health Care Authority proposes rules to set up a statewide certified community behavioral health clinic (CCBHC) model, as directed by 2025 state legislation. The rules would also set cost-based rates and standards for CCBHC certification. CCBHCs are outpatient community-based clinics that provide a comprehensive range of mental health and substance use disorder services.
- Published
- Oct 7, 2026
- Comments close
- Oct 27, 2026
How to weigh in: Comment by October 27, 2026.
WSR 26-19-140
Preprint, not peer-reviewedbioRxiv
Human CD4 T cells can control tumors indirectly, preprint suggests
A preprint, not yet reviewed by other scientists, reports that human CD4 T cells, a type of immune cell, can control tumors without recognizing the tumor directly, by acting through antigen presenting cells. In humanized mice, transferring the T cells caused regression of HLA-DP-negative tumors, and that control needed HLA-matched human antigen presenting cells. The authors say this could matter for cancers whose tumor cells lack major histocompatibility complex (MHC) class II expression.
- Published
- Oct 7, 2026
DOI 10.64898/2026.09.30.755788
Preprint, not peer-reviewedbioRxiv
Artesunate reduces spread of lung cancer in mice, preprint reports
A preprint, not yet reviewed by other scientists, reports that artesunate reduced metastatic burden in mice with lung adenocarcinoma while leaving primary tumor growth unaffected. The authors say artesunate induced oxidative stress, and that metastasis-derived cells, which have altered redox balance, were especially sensitive when glutathione synthesis was also inhibited. They describe glutathione-dependent redox homeostasis as a metabolic vulnerability in metastatic cells.
- Published
- Oct 7, 2026
DOI 10.64898/2026.10.06.755294
Preprint, not peer-reviewedmedRxiv
Genetic study suggests ADHD links to personality traits run in both directions
A preprint, not yet reviewed by other scientists, uses genetic data and Mendelian randomization to test the direction of links between ADHD and the Big Five personality traits. It suggests that higher genetic liability to neuroticism and extraversion, and lower liability to conscientiousness, raise ADHD risk, while ADHD genetic liability is linked to lower agreeableness. The authors say these results support a vulnerability model for some traits and a scar model for agreeableness.
- Published
- Oct 8, 2026
DOI 10.64898/2026.10.05.26363336
Preprint, not peer-reviewedmedRxiv
Fibromyalgia-like symptoms remain common after Long COVID, preprint reports
A longitudinal cohort study, a preprint not yet reviewed by other scientists, followed people with Long COVID for a further 12 months. It found that symptoms overlapping with fibromyalgia remained common, with 67.5% to 78.6% meeting the symptom-based criteria at each point of follow-up. The authors say the findings support closer integration of Long COVID and chronic pain rehabilitation services.
- Published
- Oct 8, 2026
DOI 10.64898/2026.10.07.26364942
Preprint, not peer-reviewedmedRxiv
Preprint estimates genetic risk scores account for disease burden in Taiwan
A preprint, not yet reviewed by other scientists, estimates how much non-communicable disease burden in Taiwan can be attributed to polygenic risk scores, linking Taiwan Biobank and National Health Insurance Research Database data. It reports the strongest genetic-risk associations for atrial fibrillation and gout. It also links a top-decile integrated polygenic risk score (iPRS) to 23.9% more hospital days and 19.1% more inpatient visits.
- Published
- Oct 9, 2026
DOI 10.64898/2026.10.07.26365010
Preprint, not peer-reviewedbioRxiv
New single-cell method profiles 29 prostate cancers, preprint reports
A preprint, not yet reviewed by other scientists, describes scPRIME-seq, a method that profiles transcriptome, genome and DNA methylome simultaneously in single cells. It was applied to 436,908 cells from 29 prostate cancers and 15 benign tissues. The authors report early focal epigenetic changes present in founder aneuploid clones and benign tissues, which they describe as a pre-neoplastic origin of epigenetic burden.
- Published
- Oct 9, 2026
DOI 10.64898/2026.10.07.757464
Preprint, not peer-reviewedbioRxiv
Mouse study links cancer cachexia behavior changes to tryptophan metabolism
A preprint, not yet reviewed by other scientists, reports mouse studies of pancreatic cancer cachexia, which the authors describe as pathological weight loss with anorexia and depressive symptoms. The authors link its behavioral and feeding problems to altered tryptophan metabolism, which depletes serotonin and accumulates kynurenine. Restoring serotonin activity normalized feeding, locomotion and depression-like behavior in the mice, but did not change wasting, tumor burden or survival.
- Published
- Oct 9, 2026
DOI 10.64898/2026.10.08.757616
Preprint, not peer-reviewedbioRxiv
Postpartum period linked to stronger maternal antiviral immunity, preprint reports
A preprint, not yet reviewed by other scientists, reports experiments on dams showing that the postpartum period is a state of enhanced antiviral immunity. Dams infected with influenza A virus (IAV) before weaning survived more often and had less disease than nonpregnant females after a lethal challenge. The authors link the protection to the transition into lactation, and say it extended to highly pathogenic avian influenza.
- Published
- Oct 10, 2026
DOI 10.64898/2026.10.02.756285
Preprint, not peer-reviewedbioRxiv
Preprint links diet-dependent gene effects to recent human evolution
A preprint, not yet reviewed by other scientists, combines genome-wide gene-environment interaction maps with allele-frequency trajectories over about the last 10,000 years to test whether environment-responsive variants contributed to recent human adaptation. Three of 45 independent loci showed significant signs of directional selection, and the selection-linked loci were enriched for interactions involving meat and cheese consumption. The authors suggest gene-environment interactions are an important, previously underappreciated part of recent human evolution.
- Published
- Oct 11, 2026
DOI 10.64898/2026.10.05.756704
Preprint, not peer-reviewedbioRxiv
AI model maps how genetic variants affect gene activity in developing brains
A preprint, not yet reviewed by other scientists, describes Seal, an interpretable artificial intelligence (AI) transfer learning framework that models gene expression and variant effects in the developing human brain across 26 brain regions, 30 cell types and seven developmental stages. Applied to genome-wide association studies, it points to cell types and developmental windows relevant to six neuropsychiatric conditions. In autism whole-genome data, it finds a burden of de novo regulatory variants in transient fetal excitatory neurons.
- Published
- Oct 11, 2026
DOI 10.64898/2026.10.09.757610