Plain words, straight from the source. Every item links to the original document. No news outlets, no hot takes.
This is a preprint on bioRxiv, not yet reviewed by other scientists. It reports that BNIP3L/NIX-mediated mitophagy, a pathway for mitochondrial clearance, limits Alzheimer disease (AD) pathology and preserves neuronal function in human neurons, in C. elegans and in mouse neurons.
This is a temporary emergency rule from the Washington Health Care Authority, in effect from October 1, 2026. It applies a federal change so that the definition of qualified noncitizens covers only lawful permanent residents, Cuban/Haitian entrants and compact of free association migrants for federally funded medical assistance. It also lengthens the refugee medical assistance eligibility period from four months to eight months.
How to weigh in: No comment period: this is a final rule.
This is a final rule from the Washington Department of Social and Health Services, effective November 1, 2026. It updates which types of income the department does not count when working out benefits for the RCA program, to follow federal regulations and to make other clarity and policy changes. Related emergency rules are currently in place.
How to weigh in: No comment period: this is a final rule.
This is a temporary emergency rule from the Washington Department of Social and Health Services, which took effect October 1, 2026. It applies annual updates from USDA FNA for the upcoming federal fiscal year to the basic food program's standard deduction, shelter and utility deductions, resource limit, and minimum and maximum allotments. The department is also proceeding with permanent rule making.
How to weigh in: No comment period: this is a final rule.
This is a proposed rule from the Washington Department of Health. It would amend chapter 246-70 WAC to align medical cannabis rules with changes to state law from 2SHB 1210 in 2022 and SHB 1453 in 2024, updating terms, label requirements and tax exemptions for medical cannabis products. The department says the changes would help it uphold standards that protect public safety.
How to weigh in: Comment by November 10, 2026.
This is a proposed rule from the Washington Department of Health, phase 2 of a board's comprehensive review of chapter 246-840 WAC. Under RCW 43.70.041, the board must review its rules at least once every five years to simplify, streamline and improve them.
How to weigh in: Comment by October 23, 2026.
A peer-reviewed study in PNAS analyzed complete genome assemblies from 151 clinical isolates of Mycobacterium tuberculosis (Mtb). It finds diversity hotspots driven by gene conversion between homologous genes, with over 300 gene conversion events, mostly in virulence-associated PE, PPE and ESX gene families, including the vaccine candidate PPE18.
This is a preprint on medRxiv, not yet reviewed by other scientists. It estimates that Denmark's combined national testing and contact tracing program identified on average about 55 to 60% of infected people in the period studied. It says the program as typically implemented was largely ineffective in controlling the pandemic, though a focused approach helped control one large local outbreak.
This is a preprint on bioRxiv, not yet reviewed by other scientists. It describes hEVO, a genomic foundation model trained on haplotype sequences from whole genome sequencing data for 63,809 individuals. The authors report that it ranked first in 18 of 19 primary comparisons with other genomic models, including Evo 2.
This is a preprint on bioRxiv, not yet reviewed by other scientists. It reports possible new translation readthrough inducing drugs (TRIDs) for premature termination codon (PTC) diseases, including three Sartans, angiotensin II receptor blockers that are FDA-approved for hypertension. In a laboratory test the Sartans were more potent than ataluren, and the authors suggest these compounds might be more effective than ataluren for some of these diseases.
A peer-reviewed study in Science tests frontier language models on sequential diagnosis, where information and tests are selected step by step. In a controlled benchmark, an artificial intelligence (AI) system reached 83.2% accuracy on New England Journal of Medicine clinicopathological conference cases and 80.3% on MIMIC-IV-ED emergency department admissions, compared with 36.1% and 46.8% for generalist physicians.
A peer-reviewed study in Cell reports that taurine levels rise with age in mice and humans. In aged mice, boosting taurine further increased health span and dampened inflammation through its regulation of the NLRP3 inflammasome in macrophages. The findings come from mice.
A peer-reviewed study in PNAS estimates the causal effect of education on Alzheimer's Disease and Related Dementias (ADRD), using a regression discontinuity created by a compulsory schooling reform. It finds education reduces ADRD incidence, and that the reform weakened the relationship between genetics and ADRD incidence.
This is a preprint on bioRxiv, not yet reviewed by other scientists, based on experiments in A549 cells that express ACE2. The authors report that Spike-induced ACE2 clustering activates the PIEZO1 channel, which triggers lysosomal exocytosis, and that the resulting ceramide enhances cell-cell fusion.
This is a preprint on arXiv, not yet reviewed by other scientists. It proposes a publisher content marketplace that pays for individual facts or commentary, called 'lego blocks', used in artificial intelligence (AI) generated answers. It tests three payment rules using 1,974 search-engine queries about a heavily covered news episode, and reports that premium publishers receive 42% of allocated value under equal sharing, compared with 46-50% under a first-publication rule.
This is a proposed rule from the Washington Department of Labor and Industries. It would align WAC 296-155-200 on personal protective equipment (PPE) in construction with the federal Occupational Safety and Health Administration (OSHA) update, which states that PPE must fit properly to protect employees.
How to weigh in: Comment by November 23, 2026.
This is a proposed rule from the Texas Workforce Commission. It would amend Subchapter B of Chapter 813, relating to the Supplemental Nutrition Assistance Program Employment and Training, on access to employment and training activities and support services in §813.12.
How to weigh in: Comment by November 23, 2026.
This is a draft UK statutory instrument, so it would become law only if it is approved and made. It would amend the Environmental Permitting (England and Wales) Regulations 2016 on activities, including waste storage, that can be carried out in England without an environmental permit when operators meet set requirements and conditions.
A peer-reviewed study in PNAS uses multiyear observations from four oceanic regions to examine precipitation beneath clouds. It reports precipitation beneath marine stratocumulus in over 56% of cloudy columns with liquid water path below 130, rising to more than 84% above that level, and says oceanic cumulus clouds rain less often but produce larger drops.
The California Air Resources Board adopted regulations that further implement the California Climate Corporate Data Accountability Act and the Climate-Related Financial Risk Act. They define terms, set annual fee calculations and procedures, and set a first-year reporting deadline for Scope 1 and 2 emissions, and the regulation took effect October 12, 2026.
How to weigh in: No comment period: this is a final rule.
This is a proposed rule from the Railroad Commission of Texas on anthropogenic carbon dioxide (CO2) storage facilities and injection wells, and on multiple or alternative uses of wells. The excerpt, which is mostly rule text, shows changes such as replacing 'hearing' with 'public meeting' in permit fact sheets and construction requirements for CO2 injection wells.
How to weigh in: No comment deadline is listed; see the document.
This is a preprint on ChemRxiv, not yet reviewed by other scientists. It studies how sequential chlorination and alkaline treatment change polyamide membranes used in freshwater production. The authors report the treatment more than doubles water permeance while keeping water-salt selectivity, and say this challenges the view that swelling is detrimental to selectivity.
This is a final rule from the Texas Department of Motor Vehicles, effective October 29, 2026. It amends many sections of Chapter 215, Motor Vehicle Distribution, covering licenses, franchised dealers, manufacturers, distributors and converters, general distinguishing numbers, lessors and lease facilitators, and advertising. The department says the review was meant to improve clarity and consistency, remove duplicative language and incorporate statutory changes.
How to weigh in: No comment period: this is a final rule.
This is a temporary emergency rule from the Washington Department of Fish and Wildlife, which took effect September 28, 2026. It classifies golden mussels (Limnoperna fortunei), an invasive species established in California, as a prohibited level 1 species, which provides authority to prevent their possession, transport and introduction while permanent rule making continues.
How to weigh in: No comment period: this is a final rule.
This is a temporary emergency rule from the Washington Department of Fish and Wildlife, in effect from October 2, 2026. It repeals current emergency wildfire rules in Eastern Washington, but keeps the same rules, except the firearms and target practicing rule in WAC 220-500-140, in place for Benton, Franklin, Kittitas, Yakima, Adams, Chelan, Douglas, Grant and Okanogan counties, where fire danger is still elevated. The department does not plan permanent rule making on this topic.
How to weigh in: No comment period: this is a final rule.
This is a temporary emergency rule from the Texas Parks and Wildlife Department, which took effect October 8, 2026. It reinstates deer season, bag limit and restriction provisions for white-tailed deer that were inadvertently removed during recent rulemaking. The department says it will address the issue through normal rulemaking before the 2027-2028 deer seasons.
How to weigh in: No comment period: this is a final rule.
This is a proposed rule from the Washington Liquor and Cannabis Board on how alcohol products are placed within retailers that sell alcohol for off-premises consumption. The board says the purpose is to reduce product confusion, theft and youth exposure.
How to weigh in: Comment by December 4, 2026.
This is a preprint on ChemRxiv, not yet reviewed by other scientists. It describes a bionic computing design built from an information metasurface array, and the authors aim it at the energy demands of artificial intelligence (AI) and robotics.
A peer-reviewed study in PNAS reports economic experiments in which participants traded with others, and found that diverse groups underperformed when the best trades required cross-race exchange. A brief linguistic intervention that gave participants a communicative toolkit increased communication and restored cross-race trade and specialization, closing the performance gap. The authors report its effects were minimal when efficient trade did not need to cross race.
A peer-reviewed study in Science describes an implantable, wirelessly powered electrocatalytic closed-loop health optimization (ECHO) device that oxidizes blood glucose to gluconate, which the kidneys clear. In type 2 diabetic mice, activating the device restored glucose balance within 1 hour and reduced body weight and triglycerides over 6 weeks, with no detectable hypoglycemia.
A peer-reviewed study in Science reports a decoupled deposition strategy for self-assembled monolayers and perovskite on flexible substrates, aimed at improving flexible perovskite solar modules (PSMs). The certified power conversion efficiency (PCE) was 20.2% on modules of 750 cm², and a 22.0% device lost 8% after 1044 hours under maximum power point tracking at 85°C and 65% relative humidity.
This is a preprint on arXiv, not yet reviewed by other scientists. It introduces continual validation, which tests each proposed version of an artificial intelligence (AI) analyst before deployment using simulated data under the null hypothesis. The authors report Type I error rates reached 0.098 and 0.183 without it, and at most 0.045 and 0.044 with it, while retaining 82% and 96% of the power from optimally selected valid updates.
This is a preprint on arXiv, not yet reviewed by other scientists. It proposes an online method for deciding whether to accept an artificial intelligence (AI) decision automatically or send it to an expert auditor, aiming to minimize auditing while keeping the share of unaudited AI errors below a set threshold. The authors report valid error control in tests on screening harmful requests to large language models, qualitative text annotation and data labeling.
This is a preprint on ChemRxiv, not yet reviewed by other scientists. Using operando X-ray nano-tomography, it tracks pore formation in lithium metal electrodes under stack pressure. The authors suggest that a homogeneous initial lithium deposition in each cycle should be targeted to suppress pore trapping.
This is a temporary rule from the Washington Department of Children, Youth, and Families, in effect from October 1, 2026. It amends WAC 110-15-0075 on income eligibility and copayment amounts for the working connections child care (WCCC) program to comply with ESSB 5752.
How to weigh in: No comment period: this is a final rule.
This is a proposed rule from the Washington Department of Commerce, implementing HB 2338, a 2026 law that lets the department use existing low-income weatherization funds for community scale projects covering multiple dwelling units in one neighborhood or area. Those projects need not have all units occupied by low-income residents, but the department must prioritize projects that serve low-income households.
How to weigh in: Comment by November 12, 2026.
The Federal Retirement Thrift Investment Board issued this final rule, published October 22, 2026, on court orders and legal processes that affect Thrift Savings Plan accounts. The document does not state when the rule takes effect or describe its details.
How to weigh in: No comment period: this is a final rule.